Fasting for Rheumatoid ArthritisYouTube↗  IA↗(long shot)
Science & Technology  20.8K views 871 likes 11 dislikes   09 Dec 2020
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"Fasting for Rheumatoid Arthritis"
Alan Goldhamer is the founder of the TrueNorth Health Center
Faste og rheumatoid arthritis Oversat af Dorte Fløjgaard Alan Goldhamer er grundlæggeren af TrueNorth Sundhedscenter
in Santa Rosa, California, which has fasted 10,000 people for conditions
i Santa Rosa, Californien, som har testet faste hos 10.000 patienter
ranging from diabetes and cardiovascular disease to autoimmune diseases.
med alt fra diabetes og hjerte- og kar- sygdomme til autoimmune sygdomme.
He noted that conditions that seem to be tied to dietary excess
Han siger at sygdomme som virker som om de er koblet til ernæringsoverflod
tend to respond predictably to the use of fasting
har en tendens til at reagere forudsigelig ved brug af faste
followed by a health-promoting diet, which he describes as a low salt,
efterfulgt af en sundhedsfremmende diæt, som han beskriver som en lav-salt,
all plant, high fiber, low fat, low protein, and low sugar diet.
kun planter, høj fiber, lav fedt, lav protein og lav sukker diæt.
This approach offers people an option to eliminate the cause
Denne tilgang tilbyder mennesker muligheden for at fjerne årsagen
of lifestyle diseases often to the point where the medication
til livsstilssygdomme ofte til det punkt hvor medicin
is no longer needed, in contrast to conventional medicine,
ikke længere er et behov, til forskel til konventionel medicin,
which is more about the suppression of the symptoms
som handler mere om at undertrykke symptomerne
associated with the disease, rather than removing the underlying root cause.
tilknyttet til sygdommen, end at fjerne den underliggende årsag.
Goldhamer put it this way: If you treat high blood pressure
Goldhamer siger det på denne måde: Hvis du behandler højt blodtryk
or type 2 diabetes or autoimmune disease medically, they'll tell you,
eller type 2 diabetes eller autoimmune sygdomme medicinsk, siger de til dig,
"You'll be on these medications the rest of your life."
"Du er på denne medicin resten af dit liv."
That’s them in effect promising you, if you follow their advice
De lover dig, hvis du følger deres råd
to the letter, “you will be sick the rest of your life.”
til punkt og prikke, "at du vil være syg resten af livet."
Preliminary data suggests fasting may benefit metabolic diseases,
Indledende data foreslår at faste gavner metaboliske sygdomme,
pain syndromes, high blood pressure, chronic inflammatory diseases,
smertesymptomer, forhøjet blodtryk, kronisk inflammatoriske sygdomme,
allergic diseases, and psychosomatic disorders,
allergier og psykosomatiske lidelser,
but the highest level of evidence we have for the benefits of fasting
men det højeste niveau af beviser vi har med fordelene ved at faste
are in regards to rheumatic diseases:
er i forbindelse med rheumatoid sygdomme:
autoimmune inflammatory joint diseases, like rheumatoid arthritis.
autoimmun inflammatorisk ledsygdomme ligesom rheumatorisk gigt.
Nearly a century ago it was written that “diet treatment
For næsten et århundrede siden blev det skrevet at "kost behandling
is not generally recognized by the medical profession…
er ikke generelt anerkendt af det medicinske erhverv...
as one of the weapons with which to attack [such diseases].”
som et af de våben man angriber [sådanne sygdomme]."
This attitude persisted until relatively recently,
Denne attitude bestod indtil for nylig,
but a systematic review of controlled trials has since
men en systematisk anmeldelse af kontrollerede forsøg har sidenhen
“shown a statistically and clinically significant beneficial long-term effect.”
"vist en statistisk og klinisk overbevisende fordelagtig langtidseffekt."
Rheumatoid arthritis has a well-known genetic component,
Rheumatoid arthritis har en velkendt genetisk bestandel,
but the concordance rate, the chance that a pair of identical twins
men overensstemmelsesraten, chancen for at et par identiske tvillinger
both get it when one has it is probably under 30%,
begge får det når en af dem har det, er formodentlig under 30%,
despite having the same genes, leaving 70%
selvom de har de samme gener, efterlader 70%
to be explained by non-genetic factors.
til at blive forklaret af ikke-genetiske faktorer.
Even if we don't know exactly what those factors are,
Selv når vi ikke ved præcist hvad disse faktorer er,
“fasting [has been compared] to rebooting the hard drive in a computer.
"at faste [har været sammenlignet] med at genstarte et program på din computer.
Sometimes, the [drive] gets corrupted
Nogle gange er programmet ødelagt
and you don’t know exactly where the problem is.
og du ved ikke helt præcis hvor problemet er.
But if you just turn it off and reboot it,…
Men hvis du slukker og genstarter den...
that corruption [may get] cleared out.”
så bliver det måske løst helt af sig selv."
The evidence base started with case reports, fasting followed by
Bevisgrundlaget startede med sager som meldte, at faste efterfulgt af
a plant-based diet, remarkable reports of years of pain and stiffness…
en plantebaseret diæt, usædvanlige fortællinger om år med smerte og stivhed...
gone within a week, and, more importantly,
som forsvinder efter en uge og hvad er mere vigtigt,
stayed gone on the healthier diet.
forblev væk på den sundere livsstil.
One after another like that, but case reports are just glorified anecdotes.
En efter en med samme resultat, men sagen er bare forgyldte anekdoter.
There have been studies  going back decades suggesting
Der er studier årtier tilbage som antyder
fasting may represent the most rapid, available way to induce relief
at faste måske repræsenterer den hurtigste tilgængelige måde at fremkalde lindring
of arthritic pain and swelling for patients who have rheumatoid arthritis,
fra gigtsmerter og hævelser hos patienter som har rheumatoid arthritis,
but the studies often failed to have control for the placebo effect,
men studierne fejler ofte i forhold til kontrolgruppen og placebo effekten,
which is especially important when it comes to relying on self-reported
som specielt er vigtig når man skal stole på selvreporterede
subjective symptoms such as pain and general well-being.
subjektive symptomer som smerter og generel trivsel.
But there are objective measures, lab tests of inflammation
Men der er objektive målinger, laboratorietest af inflammation
that don’t appear to be affected by placebos,
som ikke ser ud til at blive påvirket af placebo
and that’s what you can see in controlled trials,
og det er det du kan se i kontrollerede forsøg,
starting immediately and remaining down for at least a year.
som starter med det samme for fortsætter mindst i et år.
Ten different measures of inflammation significantly decreased
Ti forskellige inflammationsarter faldt markant
after the fasting and subsequent meat- and egg-free diet,
efter fasten og efterfølgende kød og æggefri diæt,
whereas none of the parameters budged in those disease victims
hvorimod ingen af parametrene forbedrede sig i de sygdomsofre
that continued to eat their regular diets.
som fortsatte med deres sædvanlig diæt.
And this squelching of inflammation translated into a significant reduction
Og disse dårlige kår for inflammationen forårsager en betydelig reduktion
in pain, morning stiffness, loss of grip strength,
af smerter, morgenstivhed, tab af gribestyrke,
and number of tender and swollen joints.
og et antal af ømme og opsvulmede led.
Even a year after the trial was over, those who benefited from the diet
Selv et år efter forsøgene var overstået, har dem som drog fordel af diæten
continued to benefit in terms of pain, stiffness,
fortsat med fordele med mindre smerter, stivhed
and tender and swollen joints,
og ømme og svulmede led,
presumably because they stuck with it.
formodentlig fordi de vedblev på diæten.
There is little doubt that while fasting both inflammation and pain
Der er lidt tvivl om at under fasten er både inflammation og smerter
are relieved, but if you go back to the same diet you were on before,
lindret, men hvis du går tilbage til den samme diæt du var på før,
the inflammation returns—unless,  evidently, the fasting period
så vender inflammationen tilbage - på nær åbenbart, fasteperioden
is followed by a vegetarian  diet. Why might that be?
er efterfulgt af en vegetarisk diæt. Hvorfor mon dette er tilfældet?
It could be due to changes in the microbiome,
Det kan være på grund af ændringer i mikroorganismerne,
the improvement in symptoms coincided with a significant alteration
hvor forbedringerne af symptomerne sammenfalder med en væsentlig ændring
of the intestinal flora, which may somehow be beneficial,
af tarmfloraen, som måske på en vis er fordelagtig,
perhaps by strengthening the gut barrier.
måske ved styrkelse af tarmbarrieren.
We know fasting can decrease the leakiness of the gut
Vi ved at faste kan formindske tarmens lækage
in rheumatoid arthritis patients, but we don’t yet know what role,
i gigtpatienter, men vi ved ikke hvilken rolle,
if any, this plays in the disease process.
hvis nogen, dette spiller i sygdomsprocessen.
It could be as simple as eicosanoids, the mediators of inflammation
Det kunne være ligeså simpel som eicosanoider formidlerne af betændelse
that are formed from arachidonic acid.
som formes af arachidonsyre.
Arachidonic acid is a long-chain inflammatory omega-6 fatty acid
Arachidonsyre er en lang kædet inflammatorisk omega-6 fedtsyre
found in animal fats.
som findes i fedt fra dyr.
The biggest contributors are chicken and eggs,
De største bidragsydere er kylling og æg,
which together contribute nearly half of American intake.
som sammen bidrager med næsten halvdelen af den amerikanske diæt.
That’s been suggested as an explanation of why those eating
Dette er blevet foreslået som en forklaring på hvorfor dem som spiser
more plant-based appear to have better mental health;
en mere plantebaseret kost ser ud til at have en bedre mental sundhed;
they’re not suffering the “cascade of neuro-inflammation”
de lider ikke under "mængden af neuro-inflammation"
caused by arachidonic acid;
forårsaget af arachidonsyre;
why removing eggs, chicken and other meat was shown in a randomized
og derfor at fjerne æg, kylling og andet kød viste i randomiserede
controlled trial to improve mood, suggesting the arachidonic acid
kontrollerede forsøg at forbedre humør, antyder at arachidonsyren
might be negatively impacting mood states and may help explain
kan påvirke humøret negativt og kan hjælpe med at forklare
the impact of more plant-based diets on inflammatory diseases
påvirkningen af de mere plantebaserede diæter i forhold til inflammatoriske
like rheumatoid arthritis.
sygdomme som rheumatoid arthritis.
So, that may help explain why maintaining a plant-based diet
Så, det kan måske forklare hvorfor det er nødvendig at opretholde
appears to be necessary “after the fast to prevent the recurrence
en plantebaseret diæt "efter fasten for at forebygge tilbagevenden
of symptoms and inflammatory activity,”
af symptomer og inflammatotisk aktivitet,"
or as one popular press article put it,
eller som en populær avisartikel skrev det,
fasting may just be a tool to get you to radically kickstart
faste er måske det redskab som får dig til radikalt at påbegynde
a change in the way you eat.
en ændring af dine spisevaner.
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