2-Minute Neuroscience: THCYouTube↗  IA↗(long shot)
Science & Technology  8.5K views 281 likes 1 dislikes   10 Jun 2020
Neuroscientifically Challenged 695K subscribers United States YouTube↗


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THC is the main psychoactive component of cannabis, and one of a class of compounds
THC ist die psychoaktive Hauptkomponente von Cannabis und eine aus einer Klasse von Verbindungen
known as cannabinoids.
bekannt als Cannabinoide.
Cannabis tends to be relatively low in THC compared to its levels of a THC precursor,
Cannabis ist in der Regel relativ THC-arm im Vergleich zu seinen Gehalten an einem THC-Vorläufer,
THCA.
THCA.
Heating the cannabis plant, however, causes the conversion of THCA to THC, which is part
Das Erhitzen der Cannabispflanze verursacht jedoch die Umwandlung von THCA in THC, die Teil ist
of the basis for heating or burning the plant for use.
der Basis zum Heizen oder Verbrennen der Anlage für den Einsatz.
The effects of cannabis may vary depending on the variety of cannabis plant and its associated
Die Wirkungen von Cannabis können je nach Situation variieren auf die Vielfalt der Cannabispflanze und die damit verbundenen
levels of THC and other cannabinoids, but common effects of THC include: euphoria, sedation,
Spiegel von THC und anderen Cannabinoiden, aber Häufige Auswirkungen von THC sind: Euphorie, Sedierung,
stimulation of appetite, impaired cognitive function, analgesia, and anxiety.
Appetitanregung, kognitive Beeinträchtigung Funktion, Analgesie und Angst.
THC is thought to exert most of its effects by binding to receptors called cannabinoid
Es wird angenommen, dass THC die meisten seiner Wirkungen ausübt durch Bindung an Rezeptoren namens Cannabinoid
receptors.
Rezeptoren.
There are two known cannabinoid receptors, CB1 and CB2---both of which are g-protein coupled
Es sind zwei Cannabinoidrezeptoren bekannt: CB1 und CB2 - beide sind g-Protein-gekoppelt
receptors.
Rezeptoren.
CB1 receptors are found throughout the nervous system, while CB2 receptors are primarily
CB1-Rezeptoren finden sich im gesamten Nerv System, während CB2-Rezeptoren in erster Linie sind
found on immune cells.
auf Immunzellen gefunden.
THC acts as a partial agonist at cannabinoid receptors, meaning it binds to these receptors
THC wirkt als partieller Agonist bei Cannabinoid Rezeptoren, was bedeutet, dass es an diese Rezeptoren bindet
and generates a response that’s a fraction of what other substances that bind to the
und generiert eine Antwort, die ein Bruchteil ist von welchen anderen Substanzen, die an die binden
receptors can generate.
Rezeptoren können erzeugen.
THC interacts with a number of other targets as well, but it’s thought that its main
THC interagiert mit einer Reihe anderer Ziele auch, aber es wird gedacht, dass es Haupt ist
psychoactive effects are mediated through its action at CB1 receptors.
psychoaktive Effekte werden durch vermittelt seine Wirkung an CB1-Rezeptoren.
Activation of CB1 receptors is thought to lead to the modulation of the release of various
Es wird angenommen, dass die Aktivierung von CB1-Rezeptoren erfolgt führen zur Modulation der Freisetzung verschiedener
neurotransmitters.
Neurotransmitter.
It’s not fully understood how this translates into the characteristic effects of THC, but
Es ist nicht vollständig verstanden, wie dies übersetzt wird in die charakteristischen Wirkungen von THC, aber
the activation of CB1 receptors in different areas of the nervous system may partially
die Aktivierung von CB1-Rezeptoren in verschiedenen Bereiche des Nervensystems können teilweise
explain the effects of the drug.
erklären die Wirkungen des Arzneimittels.
CB1 receptors in areas like the cortex and hippocampus, for example, may be involved
CB1-Rezeptoren in Bereichen wie dem Cortex und Hippocampus kann zum Beispiel beteiligt sein
in the perceptual and cognitive effects of THC. CB1 receptors in areas like the basal
in den Wahrnehmungs- und kognitiven Wirkungen von THC. CB1-Rezeptoren in Bereichen wie dem Basal
ganglia and cerebellum may be associated with sedation and effects on movement. And CB1
Ganglien und Kleinhirn können mit assoziiert sein Sedierung und Auswirkungen auf die Bewegung. Und CB1
receptors in areas like the spinal cord and brainstem may be linked to analgesic effects.
Rezeptoren in Bereichen wie dem Rückenmark und Hirnstamm kann mit analgetischen Wirkungen verbunden sein.
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